(S)-2-(1-(tert-butoxycarbonyl)piperidin-3-yl)acetic acid is an organic compound with the chemical name (S)-2-(1-(tert-butoxycarbonyl)piperidin-3-yl)acetic acid. The following is a description of its nature, use, formulation and safety information:
Nature:
(S)-2-(1-(tert-butoxycarbonyl)piperidin-3-yl)acetic acid is a solid powder with a white or white-like appearance. It is stable at room temperature and soluble in most organic solvents. Its melting point is about 60-65°C.
Use:
(S)-2-(1-(tert-butoxycarbonyl)piperidin-3-yl)acetic acid is often used as a protecting group in organic synthesis. Due to the presence of its piperidine ring and acetate group, it can protect the amino group (or keto group) on some compounds during the synthesis. This facilitates selective chemical reactions in organic synthesis.
Method:
The preparation of (S)-2-(1-(tert-butoxycarbonyl)piperidin-3-yl)acetic acid is usually carried out by the following steps: first, piperidine is used as a substrate, and a tert-butoxycarbonyl group is introduced on the piperidine ring by Schlein reaction. The tert-butanol carbonyl group is then converted to an acetoxy group by a catalytic hydrogenation reaction.
Safety Information:
(S)-2-(1-(tert-butoxycarbonyl)piperidin-3-yl)acetic acid is generally relatively safe under normal operating conditions. However, it is still a chemical substance, so proper safety measures need to be taken when handling it. This includes wearing personal protective equipment (such as gloves and goggles) and avoiding skin contact and inhalation. In addition, it should be stored in a sealed container, away from fire and oxidizing agents. Always refer to the relevant safety data sheets and operating instructions during use and storage.